In Age of Extinction, he is being hunted by both the Transformer-hating Harold Attinger and a Cybertronian assassin and bounty hunter, Lockdown, who is working for the Creators to bring him to Cybertron and kill any Autobots who refuse to give up his location. Optimus loses his right arm to Sentinel Prime at the film's climax.
The trailer contains enhanced weapons and flight gear. Optimus finally has a trailer similar to his Generation 1 counterpart, and has been redesigned to look more heroic. During the battle in Chicago, Optimus kills some Decepticons, including the Driller, Shockwave, and finally Megatron before he kills Sentinel Prime (avenging Ironhide's death). But, Sentinel later betrays the Autobots and joins the Decepticons to restore Cybertron with the Pillars. In Dark of the Moon, Optimus revives Sentinel Prime using the Matrix of Leadership and revealed he was the leader of the Autobots before him. After a vicious fight, Optimus severely wounds Megatron and kills the Fallen. Optimus Prime then faces The Fallen and Megatron. Near the end of the film, he is later revived by Sam with the Matrix of Leadership and is fused with Jetfire, making him more powerful. In Revenge of the Fallen, Optimus is killed (impaled from behind) by Megatron after a battle with him, Starscream and Grindor. Afterward, Optimus and the other Autobots form an alliance with the humans and work closely with NEST. As a result, Cybertron can no longer be restored.
At Mission City, he kills Bonecrusher and battles Megatron, but Sam pushes the AllSpark into Megatron's chest, killing him and destroying the cube. In the first film, Optimus Prime arrives on Earth with Ratchet, Ironhide, and Jazz trying to find the AllSpark. The flight gear features machine guns and missile launchers. Optimus Prime is armed with an ion blaster, a shotgun, energon blades, an energon axe, energon hooks, bladed knuckles, a shield, and flight gear. He transforms into a 1994 red and blue Peterbilt 379 semi-trailer truck in the first three films, a rusty 1973 Marmon HDT-AC 86 semi cab-over truck in the beginning of the fourth film, and later a blue and red 2014 Western Star 5700 OP Phantom semi-truck.